Gastrointestinal stromal tumors (GIST) represent rare malignancies of mesenchymal origin that can appear at any site of the gastrointestinal tract. Their classification, patient treatment and prognosis had been a source of controversy. The biology of these tumors revealed association to the type III tyrosine kinase receptor and the KIT CD117 protein expression. GIST mesenchymal lesions derive from the interstitial cells of Cajal. Classification methods include the one by Miettinen and Lasota and the ‘‘modified NIH classification’’. Histologically, the diagnosis of GIST falls into one of the following categories: spindle cell type (70%), epithelioid type (20%), or mixed type (10%). Histological diagnosis is usually performed via echoendoscopy-guided-biopsy or CT-guided percutaneous biopsy.


Panagiota Xaplanteri has graduated from Medical School, Patras University in 1999 and acquired the medical specialty of Biopathology (Laboratory Medicine) in 2007. She has completed her PhD in 2008 from Medical School, Patras University, Greece and her MSc in Health Care Management, Hellenic Open University in 2018. She has worked in the following positions:
•Senior Assistant, Department of Microbiology, University General Hospital of Patras, Patras, Greece, 29/9/2015-today
•Part time Assistant Professor, School of Rehabilitation Sciences, University of Patras, Greece, 2019-today
•Part time Lecturer/Assistant Professor, School of Sciences of Health and Care, Technological Educational Institute of Western Greece, Patras,2007-2019
•She has published more than 20 papers.